For "one-off" projects, MeSquares can be a good solution. The photo shows my 10FT8R RX using MeSquares.
These are simply snapped out and glued down to plain copper clad board. The copper clad board makes an excellent RF ground plane and the MeSquares excellent islands.
If glued down carefully (unlike mine!), a very neat layout is possible.
See www.qrpme.com .